Tag Archives: immune system
What Is Anaphylaxis ?
Anaphylaxis is the response of the immunology of a person to an allergen of which he is allergic to. When a person is exposed to that allergen then the body basophils and mast cells releases histamine, tryptase and serotonin materials and also some other vasoactive materials.
Reactions of anaphylactoid are clinically impossible to differentiate from anaphylaxis, but they are mediated by the medicine or material straightaway. Anaphylaxis can be separated into two on the basis of pathophysiology, the one is true anaphylaxis and the other is pseudo-anaphylaxis.
All the three that is the treatment, symptoms, and the death risk are similar but the first one is caused because of degranulation of mast cells treated by immunoglobulin E and the other without IgE treatment. Drugs such as morphine, tubocurare, alcuronium and atracurium usually lead to direct discharge of small amounts of histamine.
Active anaphylaxis - It is a type which can be seen naturally. When an animal or person is exposed to specific allergens after two weeks then the active anaphylaxis will be traced on exposure to the similar allergen.
Biphasic Anaphylaxis – It is a type in which there is no additional exposure to allergens and the symptoms reoccur in 72 hours. The percentage of occurrence ranges from 1 to 20% of the cases. The reason behind it can be morphine, aspirin, radio-contrast and muscle relaxants.
Passive anaphylaxis – It is type in which the passive anaphylaxis is tempted in local animals which obtain serum transfer serum on experimental basis from animals who are allergic to some allergens.